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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Assessment of in vitro particle dosimetry models at the single cell and particle level by scanning electron microscopy

Fig. 2

Representative SEM images illustrating different intercellular (ac) and cellular (df) ADs after deposition of differently sized particles for 1 h. a, d 100 nm particles with input particle concentration of 7 µg/mL, b, e 200 nm particles with input concentration of 50 µg/mL and c, f 500 nm particles with input particle concentration of 109 µg/mL. Due to their small size, 100 nm particles in d are marked in yellow for better visualization. ac SE SEM images were taken with 5 keV electron energy. df BSE SEM images were taken with 5 keV electron energy and a deceleration voltage of 1.9 kV (a) and 4 kV (e, f). Small dark rectangles are electron beam induced perturbations from previous scans. Scale bar: 5 μm

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