Fig. 5

Bar charts summarizing the effects of different substrate coatings on average ADs. ADs were determined on substrates in the absence of cells, which were either pre-coated with CCM or conditioned CCM. In parallel, intercellular and cellular ADs in the presence of A549 cells are depicted. Different particles sizes (100, 200, and 500 nm) and incubation times were assessed as indicated. Input concentrations were 7 µg/mL (100 nm), 50 µg/mL (200 nm) and 109 µg/mL (500 nm), except for the deposition of 100 nm NPs for 4 h in the presence of cells (50 µg/mL). Despite partly large individual errors, t-tests show a high statistical significance in most cases (p-values indicated by stars above bars: **< 0.01, ***< 0.001)