Fig. 11

The levels of TBARS and 8-OHdG in mouse lung tissues 3 days after nickel nanoparticle exposure. Mice were instilled intratracheally with 50 µg per mouse of Nano-Ni, or with either partially passivated (Nano-Ni–P) or carbon-coated (Nano-Ni–C) nickel nanoparticles with same molar concentration of Ni as Nano-Ni. Control mice were instilled with physiological saline. Mouse lung tissues were collected 3 days post-exposure. a TBARS level in mouse lung tissues. Data represent mean ± SE (n = 5). *p < 0.01 vs. Control; ^#p < 0.05 vs. Nano-Ni group. b 8-OHdG level in genomic DNA of mouse lung tissues. Data represent mean ± SE (n = 5). *p < 0.01 vs. Control; # p < 0.05 vs. both Nano-Ni and Nano-Ni–P groups