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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Endoplasmic reticulum stress: major player in size-dependent inhibition of P-glycoprotein by silver nanoparticles in multidrug-resistant breast cancer cells

Fig. 3

Treatment with 75 nm AgNPs sensitizes drug-resistant MCF-7/KCR cells to doxorubicin-induced apoptosis. a Cytotoxicity of doxorubicin and of doxorubicin and 75 nm AgNP combination in MCF-7/KCR cells. b Representative dot plots of AnnexinV/PI staining, and c number of apoptotic drug-resistant cancer cells following 75 nm AgNP and/or doxorubicin treatment or verapamil administration. The values are the means ± standard deviations of three independent experiments (*P < 0.03 ****P < 0.0001, Fisher’s LSD test)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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