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Table 3 IC50 (the concentration that is required for 50% inhibition of the metabolic activity of cells) and MHC10% values (minimum hemolytic concentration that caused 10% hemolysis of human red blood cells) assessed for tested peptides and their magnetic derivatives

From: Inhibition of inflammatory response in human keratinocytes by magnetic nanoparticles functionalized with PBP10 peptide derived from the PIP2-binding site of human plasma gelsolin

  IC50 (µg/mL) MHC10% (µg/mL)
PBP10 98.85 ± 6.67 6.02 ± 2.72
PBP10 + MNP@Au 169.22 ± 55.66 58.97 ± 39.31
PBP10 + MNP@NH2 94.17 ± 19.19 852.86 ± 607.82
RhB-PBP10 30.31 ± 5.30 51.12 ± 6.31
RhB-PBP10 + MNP@Au 33.91 ± 1.41 105.17 ± 67.30
RhB-PBP10 + MNP@NH2 34.42 ± 1.61 10.19 ± 1.18
RhB-PBP10-Cys 59.25 ± 11.60 72.92 ± 25.95
RhB-PBP10-Cys + MNP@Au 42.24 ± 5.76 94.76 ± 42.32
RhB-PBP10-Cys + MNP@NH2 32.76 ± 10.14 56.02 ± 2.75
MNP@Au 74.90 ± 35.28 511.17 ± 102.47
MNP@NH2 85.12 ± 22.56 707.39 ± 644.03
  1. Results are presented as the mean value calculated for 3 independent experiments ± SD