Fig. 6
a Cell viability of HUVECs; ANP promotes coagulation abnormalities based on a 3D human microvascular model: b reactive oxygen species (ROS), c malondialdehyde (MDA), d heme oxygenase-1 (HO-1), e NF-κB, f interleukin 1 (IL-1), g tissue factor, h thrombomodulin, i tissue plasminogen activator [Vc + ANP: Vitamin C-0.1 mg/ml, ANP-40 μg/ml, SP: special control-ANP (40 μg/ml) but without cells] (*P < 0.05, **P < 0.01, compared with the control, n = 5)