Fig. 8

Schematic of experimental setup using AFM. The adherent cell is indented by the AFM cantilever tip the signal changes on the photodetector are transformed from voltage to distance and used to calculate the Force and using Hertz model estimating the Young modulus. The cells are exposed to CBN, the presence of these materials in the media induce ROS production, protein adsorption, and F-actin polymerization disruption