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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice

Fig. 1

The expression changes in miR-210 after ischemia in vivo. a The schematic time course of the animal models developed by inducing ischemia for 1 h and reperfusion for 24 h. b TTC staining of 2-mm coronal brain slides; the lesion region is in dashed frames. c The neurological scores of mice receiving 1 h of MCAO and 24 h of reperfusion. The sham group was used as the control. N ≥ 3. The data are expressed as the mean ± SEM; ***P < 0.001 by Student’s t-test. d Quantitative analysis showing the relative miR-210 levels in the lesion region at different time points after reperfusion or in the sham group. N ≥ 3. The data are expressed as the mean ± SEM; ****P < 0.0001, and **P < 0.01, compared with the sham group by one-way ANOVA

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