Fig. 1

MWCNT induced lung injury and fibrosis in mice. Mice received DM (50 μL) or MWCNT (40 μg/50 μL DM) and were killed on days 1, 3, 7, and 14 post-exposure. a Pathological effects of lung tissues were evaluated by H&E staining (×200), bars = 20 μm. b Collagen fbers were detected in blue color by Masson’s trichrome staining (×200), bars = 20 μm. c Lung pathology score in H&E stained samples. d Quantification of lung fibrosis on histological specimens was performed using a numerical scale. Data represented the mean ± SEM (n = 6). *p < 0.05, versus control group