From: Nanocomposites as biomolecules delivery agents in nanomedicine
Type of nanomaterial | Targeting ligand | Justification | Efficacy test | References |
---|---|---|---|---|
GO/Pluronic F127 | FA Cyclic RGD peptide | Photothermal therapy | KB cells | [192] |
GO nanosheets/Poloxamer 188 | Cyclic arginine–glycine–aspartic acid–tyrosine–lysine pentapeptides | Combretastain chemotherapy | HeLa cells | [193] |
Graphene QDs | RGD peptide | DOX | U251 glioma cells | [194] |
PEG/PLGA micelles | Stapled RGD | Paclitaxel chemotherapy BBB penetration | U87 cells HUVEC cells BALB/c nude mice | [195] |
Lipid-coated PEG/PLGA | RDG peptide | Sorafenib and quercetin chemotherapy | HCC cells BALB/c nude mice | [196] |
PAMAM | IL-6 antibody RGD peptide | DOX chemotherapy | HeLa cells | [118] |
PEI-cyclodextrin-poly γ-glutamic acid | Gamma-glutamyl transpeptidase RDG peptide monensin | Targeting extrinsic apoptosis via TRAIL signalling | HCT8/ADR cells HCT8/ADR tumour-bearing BALB/c nude mice | [197] |
PEG/poly(ε-caprolactone) micelles | Cyclic RGD peptide | DOX chemotherapy | U87MG cells Nude mice | [29] |
Se/chitosan | RGD peptide | DOX chemotherapy | HUVEC cells C57BL/6 mice | [198] |