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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Silica nanoparticle-exposure during neuronal differentiation modulates dopaminergic and cholinergic phenotypes in SH-SY5Y cells

Fig. 2

Representative immunofluorescence microscopy images showing the morphology of SH-SY5Y cells on day in vitro (DIV) 7, stained with b-3-tubulin (green). Cells were kept undifferentiated (AD), differentiated with retinoic acid (RA) (EH) or staurosporine (ST) (IL). Control images, unexposed to NPs, are shown in A, B and C. SH-SY5Y cells exposed to (2.6 × 1010 NPs/ml) SiPCL-NPs (red) for 24 h at DIV1 are depicted in B, F and J. SH-SY5Y cells exposed to NPs at DIV4 are shown in C, G and K and exposure at DIV6 in D, H and L. Nuclei are shown in blue. Magnification ×630, scale bar = 50 μm

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