Fig. 2
Effects of TMZ and TMZ/PSi NPs combined with PTT and HBO on glioma stem cell viability. a Viability of NCH-421K cells after treatments with different TMZ concentrations (n = 5; **P < 0.01). b Viability of NCH-421K cells after different treatments (n = 5; *P < 0.05, **P < 0.01, ***P < 0.001). c, d Tumorsphere size and shape after different treatments (n = 5; ***P < 0.001). NCH-421K cells were cultured in normoxia and then treated under 100% O2 for 90 min/day after adding drugs. After incubation for 72 h, CCK-8 or SRB method was used to evaluate the cell viability. Bar: 50 μm