Fig. 1

Formulation and size distribution of PLGA nanoparticles containing PS-155 and nuclear localization sequence (NLS). a PLGA nanoparticles were formulated using PLGA double emulsion/solvent evaporation technique. Particles were either encapsulated with PS-155 alone or co-encapsulated with NLS and PS-155. For imaging studies, TAMRA dye conjugated PS-155 were used. b Representative size distribution and scanning electron micrographs (SEM) (inset) of PLGA nanoparticles containing PS-155. Bar represents 1 μm. Average particle diameter and SD are given for nanoparticle batch