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Table 2 Characterization of PLGA NP2 preparations containing PS-155 and PS-21 alone as well as in combination with NLS for mean size (DLS diameter), surface charge (zeta potential) and polydispersity index (PDI)

From: Investigation of PLGA nanoparticles in conjunction with nuclear localization sequence for enhanced delivery of antimiR phosphorothioates in cancer cells in vitro

PLGA polymer (NP2)

Zeta potential (mv ± SD)

DLS size (nm) ± SD

PDI

PS-155

− 26.5 ± 2.0

376 ± 15

0.16 ± 0.05

PS-155 + NLS

− 23.0 ± 1.3

355 ± 24

0.15 ± 0.04

PS-21

− 32.8 ± 1.8

357 ± 7

0.38 ± 0.04

PS-21 + NLS

− 26.2 ± 2.0

333 ± 9

0.13 ± 0.05