Fig. 5

Time-evolution of PS NP loading by HPCs (a) and THP-1 (b) cells demonstrated as median fluorescence intensity obtained by flow cytometry. Both cell types were pre-incubated with 0.83 U/ml neuraminidase before exposure to 50 µg/ml of 40 nm PS NPs, and were compared to cells only exposed to PS NPs. Mean and standard deviation of HPC cultures obtained from 3 different cord blood samples (a) and of 3 THP-1 cultures with different passage number are shown (b). Two-tailed, paired t-test: *p-value < 0.05; **p-value < 0.01