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Table 2 Main parameters of various formulations after administration in rabbit’s eye (n = 4)

From: Liposomes for effective drug delivery to the ocular posterior chamber

Parameter CBs CBLs P-CBLs
AUC (0–t) (ng/mL) 40,780.94 ± 9715.737 54,294.446 ± 13,066.52 67,033.93 ± 9105.516**
AUC (0–∞) (ng/mL) 43,825.184 ± 10,967.05 61,824 ± 45,069.22 12,314.38 ± 69,431.46*
Tmax (min) 45 ± 10 80 130 ± 47.61
Cmax (ng/mL) 323.9 ± 121.4 556.895 ± 56.859* 400.023 ± 108.757*#
t1/2z 131.442 ± 162.889 2326.416 ± 4563.18 241.006 ± 168.415
  1. * P < 0.05, ** P < 0.01, compared with CBs; # P < 0.05, compared with CBLs