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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Polyanionic carbosilane dendrimers as a new adjuvant in combination with latency reversal agents for HIV treatment

Fig. 6

Reactivation profile of BRY, PST, RMD and PNB in combination with G1-S4 (10 µM), G2-S16 (10 µM), G3-S16 (1 µM) dendrimers. J89GFP (a) and THP89GFP (b) cell lines were treated with BRY (100 nM), PST (20 µM), RMD (20 nM) and PNB (40 nm), either alone or in combinations with dendrimers for 24 h and 48 h. The integrated mean fluorescence intensity (iMFI, percentage of GFP expressing cells *MFI) of live cells was used as a measure of HIV-1 reactivation. NT non-treated control, BRY bryostatin, PST prostratin, RMD romidepsin; PNB panobinostat. The mean values (mean ± SD) of two or three independent experiments are shown (*p < 0.05; **p < 0.005; ***p < 0.001)

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