Fig. 1
From: High drug-loading gold nanoclusters for responsive glucose control in type 1 diabetes
Schematics of synthesis and responsive insulin release of gold nanoclusters (AuNCs). a Synthesis of AuNCs. b Conversion of amino group into carboxyl group on the surface of AuNCs. c Grafting of phenylboronic acid (PBA) molecule onto AuNCs to obtain AuNC-PBA. d Grafting of G-Insulin onto AuNC-PBA to achieve glucose-responsive insulin-releasing AuNC-PBA-Ins complex. e Mechanism of insulin release from AuNC-PBA-Ins for glucose regulation