Fig. 5
From: Functionalized MoS2-erlotinib produces hyperthermia under NIR
The intracellular uptake of MoS2-SS-HA using FITC as a fluorescent probe. Confocal fluorescence images (a) and quantitative flow cytometric analyses (b) of A549, H1975, PC-9, and HELF cells which were incubated with MoS2-SS-HA-FITC for 2 h (“+HA” means pretreat with 5 mg/mL HA for 2 h). Intensity of FITC fluorescence was obviously decreased with pretreatment of HA, demonstrating the HA-mediated intracellular uptake. A549 (EGFR wide-type, erlotinib-initially resistant), H1975 (EGFR-mutated subtype, L858R/T790M double mutations, erlotinib-acquired resistant) and PC-9 (EGFR-mutated subtype, exon 19 deletion, erlotinib-sensitive). The bar represents 25 μm