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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Lipid–peptide bioconjugation through pyridyl disulfide reaction chemistry and its application in cell targeting and drug delivery

Fig. 5

Liposome fusion assay of GALA-decorated POPC liposomes. a Fusion assay of GALA-decorated POPC liposomes at pH 8 and pH 5.5. The fusion was monitored through the change of the fluorescence intensity form encapsulated calcein at a self-quenching concentration of 100 mM. Total calcein release was monitored by the addition of Triton X-100 and non-decorated POPC liposomes were used as control. b Confocal microscopy images of MEFs exposed for 6 h to 100 µM of calcein-loaded 10% of DPTE-GALA decorated POPC liposomes at 37 °C stained with Lysotraker™ RED. The Lysotraker fluorescence was imaged in the red channel. Scale bars are 10 μm

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