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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Redox/NIR dual-responsive MoS2 for synergetic chemo-photothermal therapy of cancer

Fig. 8

MoS2–SS–HA–CPT for synergetic chemo-photothermal cancer therapy in vivo. (i) PBS, (ii) CPT, (iii) MoS2–SS–HA + NIR, (iv) MoS2–SS–HA–CPT, and (v) MoS2–SS–HA–CPT + NIR. a In vivo thermal images of A549 tumor-bearing mice injected intravenously with PBS, CPT, MoS2–SS–HA, and MoS2–SS–HA–CPT under NIR irradiation. b Temperature changes in tumors in groups (i), (ii), (iii), and (v) during NIR irradiation. c Body weights of mice in each group as a function of time. d Tumor growth curves of each group after various treatments. Significant differences appeared between the MoS2–SS–HA–CPT + NIR group and the other groups and are marked as **p < 0.01. e Tumor growth inhibition ratio of the experimental groups. Significant differences appeared between the MoS2–SS–HA–CPT + NIR group and the other experimental groups and are marked as **p < 0.01. f Photographs of tumors collected from the five groups after 24 days. g Tumor weights in each group. Significant differences appeared between the MoS2–SS–HA–CPT + NIR group and the other groups and are marked as **p < 0.01. h HE images of major organs collected from mice after 24 days of intravenous administration of PBS and MoS2–SS–HA–CPT

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