Fig. 6

Immune responses after siRNA@CPG@Gold Nanoshell-based PTT. a DC maturation induced by siRNA@CPG@Gold Nanoshell-based PTT on mice-bearing MFC tumors. Cells in the tumor-draining lymph nodes were collected 72 h after various treatments for assessment by flow cytometry after staining with CD80 and CD86. b Flow cytometry assay of CD4 + and CD8 + T cells in the tumor-draining lymph nodes after siRNA@CPG@Gold Nanoshell-based PTT. C,D,E, Cytokine levels (IFN-γ, IL-2, IL-6) in sera from mice isolated at 72 h post different treatments siRNA@CPG@Gold Nanoshell-based PTT. Data are given as mean ± SD (n = 5). *P < 0.05