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Table 14 Drug delivery

From: Synthesis and biomedical applications of nanoceria, a redox active nanoparticle

S. no Name of drug Cell type Observation References
1. Carboxybenzene sulphonamide None Showed an inhibition of hCAII which is very useful in the treatment of glaucoma [115]
2. Camptothecin Human pancreatic cancer cell lines BxPC-3 cells Increase in the conc. of camptothecin-loaded nanoceria decreases the cell viability of BxPC-3 cells [147]
3. Chlorin e6 Human breast cancer cells (MCF-7/ADR) and MCF-7/ADR xenograft murine model Showed photodynamic therapy in drug-resistant breast cancer cells and tumor in vivo [148]
4. Doxorubicin Human Ovarian cancer cell lines A2780, SKOV-3, and CAOV-3 Higher cell proliferation inhibition and apoptosis compared with free DOX [116]
5. Doxorubicin and Hsp90 inhibitor ganetespib (GT) A549 cells Co-delivery of Dox and GT using Nanoceria showed more than 80% of NSCLC death within 48 h of incubation [33]
6. Curcumin Neuroblastoma cell lines: IMR-32, SMS-KAN, SK-N-AS, and LA–N-6 Induce substantial cell death in neuroblastoma cells [34]
7. Doxorubicin Human liver cancer cells (HepG2 cells) Showed a synergistic anticancer effect on cancer cells [52]