Table 14 Drug delivery
From: Synthesis and biomedical applications of nanoceria, a redox active nanoparticle
S. no | Name of drug | Cell type | Observation | References |
|---|---|---|---|---|
1. | Carboxybenzene sulphonamide | None | Showed an inhibition of hCAII which is very useful in the treatment of glaucoma | [115] |
2. | Camptothecin | Human pancreatic cancer cell lines BxPC-3 cells | Increase in the conc. of camptothecin-loaded nanoceria decreases the cell viability of BxPC-3 cells | [147] |
3. | Chlorin e6 | Human breast cancer cells (MCF-7/ADR) and MCF-7/ADR xenograft murine model | Showed photodynamic therapy in drug-resistant breast cancer cells and tumor in vivo | [148] |
4. | Doxorubicin | Human Ovarian cancer cell lines A2780, SKOV-3, and CAOV-3 | Higher cell proliferation inhibition and apoptosis compared with free DOX | [116] |
5. | Doxorubicin and Hsp90 inhibitor ganetespib (GT) | A549 cells | Co-delivery of Dox and GT using Nanoceria showed more than 80% of NSCLC death within 48Â h of incubation | [33] |
6. | Curcumin | Neuroblastoma cell lines: IMR-32, SMS-KAN, SK-N-AS, and LA–N-6 | Induce substantial cell death in neuroblastoma cells | [34] |
7. | Doxorubicin | Human liver cancer cells (HepG2 cells) | Showed a synergistic anticancer effect on cancer cells | [52] |