Fig. 2
From: Exosome-mimetic nanoplatforms for targeted cancer drug delivery
Comparison between natural exosomes and EMNs. a Size distribution measured by DLS of natural exosomes and EMNs showing that we have obtained nanoplatforms of practically the same size than natural exosomes. b Time-consuming comparison for obtaining natural exosomes from cell lines and isolation by serial ultracentrifugation, cell-derived nanovesicles (NV) and EMNs. c The number of particles obtained in 216 ml of conditioned medium (16 h) of A549 exosomes and one batch of EMNs (2′2 ml). d Encapsulation efficiencies of therapeutic model molecules comparing the loading capacity of natural exosomes and EMNs. Bar charts represent mean ± standard deviation, n = 3