Exosome-mimetic nanoplatforms for targeted cancer drug delivery

Table 1 Physicochemical properties of exosomes and EMNs

	Size (nm)^a	PdI	ZP (mV)
Exosomes from human plasma	98 ± 12	0.4	− 16 ± 1
Exosomes from cancer cell lines	91 ± 11	0.3	− 23 ± 2
EMNs	100 ± 8	0.2	− 7 ± 2
F-EMNs	110 ± 2	0.3	− 6 ± 1
EMNs + miR145	104 ± 2	0.3	− 16 ± 2
F-EMNs + miR145	113 ± 1	0.3	− 5 ± 2

Data presented as mean ± standard deviation; n = 3
PdI polydispersity index, ZP zeta potential, EMNs Exosome-mimetic nanosystems, F-EMNs functionalized EMNs with a specific integrin, miR145 microRNA-145, EMNs + miR145 EMNs loaded with miR145, F-EMNs + miR145 F-EMNs loaded with miR145
^aSize corresponds to number measurement in DLS

ISSN: 1477-3155