Table 6 Role of CDs in drug/gene delivery system
S. No. | Source molecule | Ligand attached | Drug/gene delivery | Cell type | Refs. No. |
|---|---|---|---|---|---|
1. | EDTA | Mesoporous silica nanoparticles (MSPs) | DOX | HeLa | [114] |
2. | Sorbitol and sodium hydroxide | Folic acid | DOX | HeLa | [118] |
3. | β-Cyclodextrin (βCD), oligoethylenimine (OEI) and Phosphoric acid | OEI/CD | DOX | H1299 | [115] |
4. | citric acid and o-phenylenediamine | – | DOX | HeLa, mouse fibroblast cells (L929) | [116] |
5. | Carbon nanopowder | Transferrin | DOX | Glioblastoma cells; CHLA-266, DAOY, CHLA-200 and SJGBM2 cells | [119] |
6. | Urea and citric acid | carboxyl groups on CDs | DOX | HepG2 and HL-7702 | [27] |
7. | ATP (Adenosine Triphosphate) moreover, polyethyleneimine (PEI) | Hyaluronic acid (HA) | DOX | HeLa cells | [120] |
8. | d-Glucose (2.5Â mmol) and l-glutamic acid | Polydopamine coated | DOX | HeLa | [121] |
9. | Citric acid and polyene polyamine (PEPA) | Â | Oxaliplatin | Hepatic cancer cells | [122] |
10. | Citric acid and ethylenediamine | – | DOX | L929, MCF-7 and CCK-8 | [117] |
11. | Citric acid and diethylenetriamine | PEG-(PAH/DMM) | Cisplatin | A2780 | [11] |
12. | Glycerol and polyethylenimine (PEI) | fc-rPEI (folate conjugated reducible PEI rPEI) | siRNA | H460 | [123] |
13. | Citric acid and tryptophan | PEI | siRNA | MGC-803 | [60] |
14. | Branched polyethyleneimine, Hyaluronic acid | Hyaluronate (HA) and polyethyleneimine (PEI) functionalized | DNA/RNA | Hela cells | [124] |
15. | Polyethyleneimine and fluorinated diglycidyl ethers | Fluorine doped | siRNA/DNA | 7702, A549 and HepG2 | [125] |
16. | Arginine and glucose | – | pSOX-9 | Chondrogenic differentiation of mouse embryonic Fibroblasts | [76] |