Fig. 4
From: A chitosan-based cascade-responsive drug delivery system for triple-negative breast cancer therapy
Cellular uptake data. a CLSM images of HUVEC and MCF-7 cells after incubation with free DOX, CS-co-PNVCL1@DOX, and CPP-CS-co-PNVCL1@DOX NPs with or without MMP-2 (equivalent DOX concentration: 50 μg/mL; scale bar = 50 μm). The DAPI-stained nuclei are blue, and DOX red. b A quantitative histogram profile of DOX cellular uptake. c The mean fluorescence intensity from DOX in HUVEC and MCF-7 cells after incubation with the different formulations, as determined using flow cytometry