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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Hollow gold nanoshells-incorporated injectable genetically engineered hydrogel for sustained chemo-photothermal therapy of tumor

Fig. 8

Anti-tumor efficiency of PC10A/DOX/HAuNS hydrogel in vivo. a Temperature changes of tumors after injected with PC10A hydrogel and PC10A/DOX/HAuNS hydrogel (100 μL) at different period of irradiation with an 808 nm laser at power density of 2.0 W cm−2; b photographs of the mice (H&E stained histological section of tumors after treatment for 1 day, the blue and pink indicated normal tissue cells and damaged tissue cells, respectively); c pictures of the tumors extracted from mice on day 12, d tumor volume and e body weight of the mice after treatment with PBS, laser irradiation, PC10A hydrogel, free DOX solution, PC10A/DOX hydrogel, PC10A/HAuNS hydrogel with laser, and PC10A/DOX/HAuNS hydrogel with laser (808 nm, 2.0 W cm−2, 9 min). n = 6, *p < 0.05, **p < 0.01, ***p < 0.001

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