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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Cerium oxide nanoparticles improve liver regeneration after acetaminophen-induced liver injury and partial hepatectomy in rats

Fig. 4

CeO2NPs stimulates cell cycle progression and NF-κB activation. a Flow cytometry of HepG2 showing cell cycle profiles from propidium iodide DNA staining after vehicle or CeO2NPs treatment (n = 5; #p < 0.01 and *p < 0.05). b Western blot for activated caspase 3 and cyclin D1 abundance from HepG2 incubated with vehicle or CeO2NPs. β-actin was used as loading control (mean ± SEM; n = 5; *p < 0.05 versus vehicle in the same experimental condition). O.D.: optical density. c Western blot for IκBα abundance from HepG2 (mean ± SEM; n = 5; *p < 0.05). d Transcription factor immunosorbent assay for NF-κB (p65) activity in HepG2 (n = 5, *p < 0.05). e Western blot for IκBα abundance in the liver vehicle and CeO2NPs-treated rats before and 3 h post-PHx (mean ± SEM; n = 5; #p < 0.01)

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