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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Intracellular tracking of drug release from pH-sensitive polymeric nanoparticles via FRET for synergistic chemo-photodynamic therapy

Fig. 5

The π–π stacking interaction between Por-PCL-PH-PEG-cRGD and EPI, a UV–vis spectra of amphiphiles of Por-PCL-PH-PEG-cRGD in methanol and water; b fluorescence spectra of EPI/Por-PCL-PH-PEG-cRGD polymeric nanoparticles in PBS and methanol, the concentration of EPI/Por-PCL-PH-PEG-cRGD polymeric nanoparticles was 20 μg/mL. The FRET effect between Por-PCL-PH-PEG-cRGD as drug carrier and EPI as antitumor drug, c the excitation and emission spectra of Por-PCL-PH-PEG-cRGD and EPI d fluorescence spectra of mixtures of EPI and amphiphiles of Por-PCL-PH-PEG-cRGD, EPI 15 μg in 1 mL DMSO; e fluorescence spectra of the mixtures of EPI and amphiphiles of Por-PCL-PH-PEG-cRGD, Por-PCL-PH-PEG-cRGD 200 μg in 1 mL DMSO; f the fluorescence spectra of EPI loaded Por-PCL-PH-PEG-cRGD polymeric nanoparticles in PBS solution (pH = 5.0) at the fixed time during EPI releasing from the nanoparticles (λex = 485 nm)

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