Fig. 3

Impact of iRGD-PS-Tam and control compounds on cell viability. Sixty thousand MCF7 or T47D cells were plated in 24 well plates coated with BSA or FN. Cells were treated for 96 h with Tam, iRGD, PS-Tam, iRGD-PS-Tam, Tam + iRGD, PS-Tam + iRGD or empty PS (PS). a, b Impact of the treatments on MCF7 and T47D cells plated on BSA. Bars represent mean ± SEM; N = 3; *p < 0.05;**p < 0.01; one-way Anova followed by Sidak’s multiple comparisons was used to compare groups, ***p < 0.001, N = 3. c, d show the effect of the treatments on MCF7 and T47D cells plated on FN. Bars represent mean ± SEM; N = 3; one-way Anova followed by Bonferroni–Sidak’s multiple comparisons was used to compare the groups *p < 0.05;**p < 0.01; ***p < 0.001