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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: iRGD-guided tamoxifen polymersomes inhibit estrogen receptor transcriptional activity and decrease the number of breast cancer cells with self-renewing capacity

Fig. 6

Homing of iRGD-PS-Tam to mouse mammary xenographs. Mice bearing s.c. MCF7 tumors were i.v. injected with iRGD + Fam-PS-Tam or iRGD-FAM-PS-Tam. After 4 h the animals were sacrificed and tumors and organs were collected and snap-frozen. Immunofluorescence staining with anti-FAM and CD31 primary antibodies was performed. Nuclei were counterstained with DAPI. Representative images tumors and organs from two independent experiments are shown. Scale bars: 100 μm

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