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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Size-dependent tissue-specific biological effects of core–shell structured Fe3O4@SiO2–NH2 nanoparticles

Fig. 5

Schematic representation of the proposed mechanism for the in vivo size effects of Fe@Si-NPs on NAD depletion. Green arrows indicate up- or down-regulation; red arrows represent activation; broken arrow indicates less known mechanisms; red T bars represent inhibition. LDH lactate dehydrogenase, NAD nicotinamide adenine dinucleotide, NAM nicotinamide, NAM N-oxide nicotinamide N-Oxide, XO xanthine oxidase, XDH xanthine dehydrogenase

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