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Table 2 IC50 values of Taxol and every PTX loaded nanomicelles on A549 and A549/PTX cells after 24 h, 48 h, and 72 h incubation (n = 5)

From: Tumor- and mitochondria-targeted nanoparticles eradicate drug resistant lung cancer through mitochondrial pathway of apoptosis

Formulation

A549

A549/ADR

Taxol

TP/PTX

TPH/PTX

Taxol

TP/PTX

TPH/PTX

24 h

18.64 ± 0.53

36.54 ± 2.31

14.79 ± 1.56

70.48 ± 2.86

47.39 ± 3.25

35.25 ± 2.54

48 h

9.44 ± 1.32

28.22 ± 2.15

6.68 ± 1.23

61.52 ± 2.30

42.87 ± 2.36

16.41 ± 1.35

72 h

4.71 ± 0.45

14.91 ± 1.65

3.07 ± 0.45

58.53 ± 1.32

32.38 ± 3.12

9.66 ± 1.25