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Table 1 Clinical chemistry and hematology parameters for THLG-EXO treated mice

From: Engineered exosomes for targeted co-delivery of miR-21 inhibitor and chemotherapeutics to reverse drug resistance in colon cancer

Groups

ALT (IU/L)

AST (IU/L)

BUN (μmol/L)

CRE (μmol/L)

WBC (109/L)

RBC (1012/L)

Platelets (1012/L)

PBS

55.6 ± 6.4

81.4 ± 12.3

1.52 ± 0.44

14.9 ± 3.1

5.7 ± 1.4

8.2 ± 0.62

1.2 ± 0.15

THLG-EXO

59.6 ± 8.7

78.7 ± 16.3

1.55 ± 0.61

17.5 ± 4.4

5.5 ± 1.1

8.5 ± 0.42

1.1 ± 0.14

  1. ALT alanine aminotransferase, AST aspartate aminotransferase, BUN blood urea nitrogen, CRE creatinine, WBC white blood cell count, RBC red blood cell count
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Journal of Nanobiotechnology

ISSN: 1477-3155

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