Fig. 1
From: Fabrication and characterization of PLGA nanoparticles encapsulating large CRISPR–Cas9 plasmid
TIPS pentacene can be used as a fluorescent marker for cell internalization. a TIPS structure, b normalized absorbance spectrum of TIPS pentacene in THF (v/v), c calibration curve of absorbance vs. TIPS pentacene concentration in THF by volume, d representative imaging flow cytometer pictures selected randomly out of 10,000 BMDM cells treated with either mock or TIPS loaded NPs demonstrates internalization of particles into the cell as indicated by red fluorescence signal