Fig. 4From: Fabrication and characterization of PLGA nanoparticles encapsulating large CRISPR–Cas9 plasmidIn-vitro DNA release profile from nanoparticles. Majority of DNA released within the first 24 h with NPs made from amine endcaps at pH 7 showing the highest level of release. DNA release profile from the particles with respect to time at pH a 7.0, b 6.0, c 4.5. % released = [mass DNA released into solution]/[initial total mass DNA encapsulated]Back to article page