Table 2 In vivo antitumor effects of different groups against 4T1 tumors in mice
Group | Dose (mg/kg) | Spleen coefficient (%) | Liver coefficient (%) | Tumor weight (g) | Inhibition rate (%) |
|---|---|---|---|---|---|
Saline | – | 5.12 ± 0.39 | 3.48 ± 0.46 | 3.54 ± 0.55 | – |
DSF solution (i.g.) | 20 | 5.19 ± 0.60 | 3.90 ± 0.47 | 3.25 ± 0.46 | 8.19 |
PTX Injection (i.v.) | 8 | 4.64 ± 0.55 | 2.93 ± 0.38 | 1.59 ± 0.06**##$$ | 55.01 |
DSF/SPC-NSps (i.g.) | 20 | 4.72 ± 0.70 | 3.02 ± 0.61 | 1.52 ± 0.132**##$$ | 57.06 |
DSF/SPC-NSps (i.v.) | 5 | 6.50 ± 0.45 | 4.46 ± 0.29 | 1.09 ± 0.21**##$$ | 69.20 |
10 | 6.06 ± 0.48 | 4.53 ± 0.32 | 0.89 ± 0.23**##$$&& | 74.80 | |
20 | 6.18 ± 0.62 | 4.48 ± 0.36 | 0.71 ± 0.17**##$$&& | 80.00 |