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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Targeting of immunosuppressive myeloid cells from glioblastoma patients by modulation of size and surface charge of lipid nanocapsules

Fig. 2

Incorporation of differently charged LNCs by leukocyte populations. a Mean and SE of three independent experiments on PBLs obtained from peripheral blood of HDs. 100 nm DiD-LNCs with different surface charge (from neutral to positive) at 50 ng/ml DiD concentration were incubated for 3 h with PBLs; DiD-LNC uptake was assessed on CD14+ (in black) and CD3+ cells (in blue). Blank-LNC samples were used as negative control. b 100 nm positively charged LNCs (+31 mV, grey) and neutral LNCs (− 3 mV, pink) were incubated with PBLs for 3 h at 50 ng/ml DiD concentration. Did+ cells by flow cytometry analysis. Mean and SE of 3 independent experiments are reported. Student t-test was performed, *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001

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