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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Iron oxides nanoparticles (IOs) exposed to magnetic field promote expression of osteogenic markers in osteoblasts through integrin alpha-3 (INTa-3) activation, inhibits osteoclasts activity and exerts anti-inflammatory action

Fig. 7

IOs alone and with combination with MF do not elicit immune response. Morphology of macrophages in all investigated groups was investigated using staining for f-actin (af). Activation of macrophages was assessed by qRT-PCR for TNF-a (g), iNOS (h), IL-1b (i) and TGF-b1 (j). Results expressed as mean ± SD. Statistical significance indicated as asterisk (*) when comparing the results between corresponding bars representing MF− and MF+ groups, and as number sign (#) when comparing to LPS MF−. **p < 0.01; ###, ***p < 0.001

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