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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Exosomal miRNA-128-3p from mesenchymal stem cells of aged rats regulates osteogenesis and bone fracture healing by targeting Smad5

Fig. 7

a The expression of miR-128-3P in fractured callus at day 14 (NC-antagomir vs miR-128-3P antagomir, P < 0.05). b, c The post-operative micro-CT reconstruction images at 2, 3 and 4 weeks. The CV and the BV/TV were increased by the miR-128-3P antagomir treatment (n = 4, NC-antagomir vs miR-128-3P antagomir, P < 0.05, scale: 1 mm). d The mRNA level of ALP, Runx2, Collagen I and Smad5 in the callus at day 28(NC-antagomir vs miR-128-3P antagomir, P < 0.05). e The results of immunohistochemistry (NC-antagomir vs miR-128-3P antagomir, P < 0.05, scale: 100 μm)

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