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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Docetaxel-loaded solid lipid nanoparticles prevent tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells

Fig. 2

a Colloidal stability of SLN-DTX over 120 days. Hydrodynamic diameter (HD), zeta potential and polydispersity index (PDI) measured by dynamic light scattering. b Storage stability study of SLN-DTX. HD, zeta potential and PDI index were analyzed after samples were incubated for 24 h at 4 °C or 37 °C (n = 3). c Nanoparticle size distribution of SLN-DTX had an average size of 120 nm and blank-SLN around 110 nm; measurements were performed using ImageJ software. Morphology of SLN-DTX and blank-SLN was assessed by transmission electron microscopy (TEM) at 100 K and in dashed line 250 K magnification. d Drug release profiles from SLN-DTX at pH 7.4 and pH 5.0 PBS at 10 days. Data are expressed as mean ± standard error of the mean (****p < 0.0001)

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