Fig. 7
a Representative flow cytometry profiles of the cell cycle phase distribution of 4T1 cells. The first peak indicates 2n DNA content in the G0/G1 phase (purple), the second peak indicates 4n DNA content in the G2/M phase (pink), and in-between the two peaks is the S phase (green). b Dot plots representing the distribution of apoptotic cells after dual staining with Annexin V-FITC (horizontal axis) and propidium iodide (vertical axis). Annexin V-FITC and propidium iodide tagged cells symbolize early apoptosis (lower right quadrant) and late apoptosis (upper right quadrant), respectively. On the right side the percentage of the cells is presented. Groups: untreated cells, SLN-DTX and DTX. Cell were treated with 10 µg/mL for 24 h. Data are presented as mean ± standard error from three experiments (*p < 0.05; ****p < 0.0001)