Fig. 8
Inhibition of tumour growth by LPPC/pRBDV/RBDV and the RBDV protein. Female C57BL/6 mice (6–8 weeks of age) were subcutaneously inoculated with 1 × 106 cells in 100 mL of PBS. When the average tumour volume reached 30 mm3, the mice were i.v. injected with LPPC/pRBDV/RBDV or RBDV protein. Inverted filled triangle means the day of complex injection. Tumour volume was measured every 2 days after injection of the complexes, and the mice were sacrificed when the tumour grew to a size of 2500 mm3. LPPC, which encapsulated with RBDV or IgG1 Fc, were all complexed by PEG. The data represent the mean ± SD (n = 7). Significant differences are evaluated by Student’s t-test and are labelled as *P < 0.05