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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage

Fig. 5

a Flow cytometry of SH-SY5Y cells treated first with Fe2+ to induce apoptosis, and then with vehicle (DMSO), free dauricine (DRC, 1 μM), blank micelles (PM, 5 μM) or dauricine-loaded micelles (DPM, 1 μM). Negative control group was treated with cell culture medium only without Fe2+, Cells were stained with annexin V-FITC and propidium iodide, then sorted by flow cytometry. b Percentage of apoptotic cells in different treatment groups. *P<0.05 (n=5)

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