Fig. 5

In vivo tumor image and antitumor effect. a–f Acquired from the HepG2 tumor-bearing nude mice that were intravenously injected with ICG-Dox-HepM-TSL, ICG-Dox-TSL and PBS under NIR irradiation (808 nm, 1 W cm⁻²). a Fluorescence image of HepG2 tumor-bearing nude mice 13 days after the intravenous injection of ICG-Dox-HepM-TSL and its counterparts. b Photos of the tumors extracted from the nude mice in (a). c Photoacoustic imaging of tumor sites in HepG2 tumor-bearing nude mice in (a). d Tumor weights of the nude mice after therapy. e Quantitative results of the HepG2 tumor relative volumes during therapy. f Body weights of the nude mice during therapy. g–l The corresponding data of (a–f) and acquired from the HepG2 tumor-bearing nude mice that were intravenously injected with ICG-Dox-HepM-TSL, ICG-Dox-TSL and PBS without of NIR irradiation