Fig. 5

a EXE concentration changes in the plasma samples of the healthy mice (n = 3) after administrations with various formulations. b–d Relative BGL changes of the db/db mice (n = 6) after administrations with various formulations. The oral EXE dose was 0.6 mg/kg and the injected EXE dose was 0.06 mg/kg in a–c; the oral EXE dose was 0.78 mg/kg and the injected EXE dose was 0.078 mg/kg in d