Fig. 6
a Relative BGL changes of the db/db mice after oral administrations with DIS NPs and COM NPs at an EXE dose of 0.6 mg/kg and subcutaneous injection with free EXE solution at a dose of 0.06 mg/kg once daily for 7 weeks consecutively. b HbA1c, c C-peptide and d insulin concentrations of the db/db mice after the 7-week treatments. e Representative insulin-immunostained images and relative β-cell areas of the histological sections of the pancreatic islets from the db/db mice after the 7-week treatments. (n = 6), P < 0.05 compared with saline group