Fig. 4
The stealth properties of RBCm-coated NPs in vitro and in vivo. a SDS-PAGE of purified RBCm-coated NPs and emptied RBC membrane-derived vesicles (control). Samples were run at equal protein concentration and stained with Coomassie Blue. b CD spectra of RBC membranes, RPCNP and T807/RPCNP NPs. c CLSM images of RAW264.7 cells after incubation with various COU-tagged formulations. Scale bars represent 20 μm. d Plasma CUR concentration–time profiles after i.v. injection of different formulations in rat. The data are presented as the mean ± SD (n = 3)