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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: RETRACTED ARTICLE: Neuron tau-targeting biomimetic nanoparticles for curcumin delivery to delay progression of Alzheimer’s disease

Fig. 5

Transport across the BBB of biomimetic formulations in vitro and in vivo. a CLSM images of HT22 cells after incubation with different COU-tagged various formulations acrossing As and RBMVEC two co-culture cells, which contain COU (green) and Hoechst 33258 (Blue, nuclear imaging). b FCM quantification of various COU-tagged (Green) formulations in HT22 cells. c In vivo brain-targeting ability. Biodistribution of DIR contained in various formulations in AD model mice determined by an IVIS® Spectrum. d The mice were sacrified and the fluorescence in various organs was detected

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